Broadly speaking, we are interested in all things mechanobiology, i.e., the role of mechanical perturbations in the evolution of mechanosignaling, structure and function, including related topics of cell adhesion, cell and matrix remodeling, and downstream changes in genotype and phenotype. Normal force sensing, remodeling and load bearing by cells are essential for basic life processes. To study these processes, our lab develops technologies to enhance maturity in human pluripotent stem cell derived cardiomyocytes (hPSC-CMs), to manipulate hiPSC-CM and other cell types in "micro physiological systems), and to make quantitative measurements of cell responses to drugs, mechanical stimuli like stiffness or stretch, or in the presence of disease mutations. Our research interests span from custom microtechnologies for small-scale mechanical measurements to questions of how mechanics mediate biological signaling. We design and fabricate most of our own tools and  custom analysis methods, and are interested in reliable and quantitative measurements of fundamental biophysics to answer novel questions in the areas of physiology, cardiology, stem cells, cell biology,  and neuroscience.